Obesity and its effect on outcome of laparoscopic Nissen fundoplication

Dis Esophagus. 2001;14(1):50-3. doi: 10.1111/j.1442-2050.2001.00157.x.


Obesity has long been suspected as predisposing to gastroesophageal reflux disease, and it has also been claimed that it is an important cause of poor outcome following laparoscopic anti-reflux surgery. This study was performed to determine the validity of this proposition. The outcome of 194 patients from an overall experience of 971 laparoscopic anti-reflux procedures was determined in this study. Patients were included if they had undergone a laparoscopic Nissen fundoplication, had completed a minimum 12 months follow-up using a structured questionnaire, and had data available for the calculation of their preoperative body mass index (BMI). Patients were divided into three groups based on BMI: normal weight (BMI < 25), overweight (BMI 25-29.9), and obese (BMI >30). The association between BMI and outcome data from their most recent follow-up was analyzed. There was no correlation between increasing BMI and a poorer overall outcome. There was a slight trend toward less satisfaction with the surgical outcome in patients of normal weight. Preoperative obesity is not associated with a poorer outcome following laparoscopic Nissen fundoplication.

MeSH terms

  • Body Mass Index
  • Contraindications
  • Female
  • Fundoplication*
  • Gastroesophageal Reflux / etiology
  • Gastroesophageal Reflux / physiopathology*
  • Gastroesophageal Reflux / surgery*
  • Humans
  • Laparoscopy*
  • Male
  • Obesity / complications
  • Obesity / physiopathology*
  • Treatment Outcome