Protein intake in patients with renal failure: comments on the current NKF-DOQI guidelines for nutrition in chronic renal failure

Semin Dial. 2001 May-Jun;14(3):150-2. doi: 10.1046/j.1525-139x.2001.00041.x.


The National Kidney Foundation Clinical Practice Dialysis Outcomes Quality Initiative (DOQI) guidelines recently recommended dietary protein intake for patients with chronic renal failure as follows: predialysis patients should receive 0.60 g/kg/day of protein and increase intake to 0.75 g/kg/day for subjects who cannot follow such a diet. For stable maintenance hemodialysis patients, the recommended protein intake is 1.2 g/kg/day, and for chronic peritoneal dialysis patients, 1.2-1.3 g/kg/day. We differ with these recommendations and believe that a dietary protein intake of 0.8 g/kg/day is appropriate for the predialysis population; an intake of 0.9-1.0 g/kg/day and 1.0-1.1 g/kg/day for maintenance hemodialysis patients and peritoneal dialysis patients, respectively, should be adequate. The rationale and the evidence supporting our arguments are outlined and discussed.

Publication types

  • Editorial

MeSH terms

  • Clinical Trials as Topic
  • Dietary Proteins / administration & dosage*
  • Female
  • Guidelines as Topic*
  • Humans
  • Kidney Failure, Chronic / diet therapy*
  • Kidney Failure, Chronic / therapy
  • Male
  • Nutritional Requirements*
  • Nutritional Status
  • Prognosis
  • Renal Dialysis
  • Sensitivity and Specificity


  • Dietary Proteins