Treatment of resistant discoid lupus erythematosus of the palms and soles with mycophenolate mofetil

J Am Acad Dermatol. 2001 Jul;45(1):142-4. doi: 10.1067/mjd.2001.114297.


Mycophenolate mofetil is an immunosuppressive drug that has recently been used to treat a variety of autoimmune and inflammatory skin diseases. Expanding the use of this agent in dermatology, we describe 2 patients with both systemic lupus erythematosus and discoid lupus erythematosus whose recalcitrant palmoplantar lesions were successfully treated with mycophenolate mofetil.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Drug Resistance
  • Female
  • Foot Diseases / drug therapy
  • Foot Diseases / pathology
  • Hand / pathology
  • Humans
  • Immunosuppressive Agents / pharmacology
  • Immunosuppressive Agents / therapeutic use*
  • Lupus Erythematosus, Discoid / drug therapy*
  • Lupus Erythematosus, Discoid / pathology
  • Mycophenolic Acid / analogs & derivatives
  • Mycophenolic Acid / pharmacology
  • Mycophenolic Acid / therapeutic use*
  • Recurrence


  • Immunosuppressive Agents
  • Mycophenolic Acid