Syphilis fast latex agglutination test, a rapid confirmatory test

Clin Diagn Lab Immunol. 2001 Jul;8(4):841-2. doi: 10.1128/CDLI.8.4.841-842.2001.


Using 255 serum samples with various reactivities, we evaluated the Syphilis Fast latex agglutination test (Syphilis Fast) against the Treponema pallidum particle agglutination test (TP-PA) for confirming a diagnosis of syphilis. We found 98.8% agreement between the Syphilis Fast and the TP-PA. The Syphilis Fast, however, had a couple of advantages over the TP-PA: the test takes only 8 min to perform and produces results that are easy to read. It appears to be a good confirmatory test for syphilis, especially for point-of-care clinics such as prenatal or sexually transmitted disease clinics.

Publication types

  • Comparative Study

MeSH terms

  • Agglutination Tests / methods
  • Humans
  • Latex Fixation Tests / methods*
  • Reagent Kits, Diagnostic*
  • Sensitivity and Specificity
  • Syphilis / blood
  • Syphilis / diagnosis*
  • Syphilis / immunology
  • Syphilis / microbiology
  • Time Factors
  • Treponema pallidum / immunology
  • Treponema pallidum / isolation & purification


  • Reagent Kits, Diagnostic