Phosphopeptides and gamma-carboxyglutamic acid-containing peptides in calcified turkey tendon: their absence in uncalcified tendon

Calcif Tissue Int. 1979 Jul 3;27(3):281-4. doi: 10.1007/BF02441198.

Abstract

Uncalcified samples of turkey tendon obtained prior to calcification, and other samples from areas of tendon that never calcify, contain little or no O-phosphoserine [Ser(P)], O-phosphothreonine [Thr(P)] and gamma-carboxyglutamic acid (Gla). Significant amounts of all three of these Ca2+-binding amino acids, which are found in EDTA-extractable, non-collagenous proteins, are detected coincident with the onset of mineralization of a tendon and increase in concentration as mineralization proceeds.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • 1-Carboxyglutamic Acid / analysis*
  • Aging
  • Animals
  • Female
  • Glutamates / analysis*
  • Organophosphorus Compounds / analysis
  • Peptides* / analysis
  • Phosphopeptides / analysis*
  • Serine / analysis
  • Tendons / growth & development*
  • Threonine / analysis
  • Turkeys

Substances

  • Glutamates
  • Organophosphorus Compounds
  • Peptides
  • Phosphopeptides
  • Threonine
  • Serine
  • 1-Carboxyglutamic Acid