Vitamin D deficiency in Iranian mothers and their neonates: a pilot study

Acta Paediatr. 2001 May;90(5):577-9.

Abstract

We conducted a pilot study to assess the prevalence of hypovitaminosis D among Iranian women and their newborns. Blood samples were taken from 50 mothers (age 16-40 yr) and their neonates at term delivery in the largest Tehran hospital. The results showed that 80% of the women had 25-hydroxyvitamin D (25-OHD) concentrations of less than 25 nmol/l. Mean maternal plasma calcium and phosphatase alkaline concentrations were in the normal range. The mean maternal serum immunoreactive parathyroid hormone concentration of women with hypovitaminosis D (i.e., 25-OHD levels <25 nmol/l) was above normal range and significantly different from that of women without hypovitaminosis D.

Conclusion: The mean cord serum 25-OHD concentration was very low (4.94+/-9.4 nmol/l) and that of infants of mother with hypovitaminosis D were almost undetectable (1.2+/-1.2 nmol/l).

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Alkaline Phosphatase / blood
  • Calcium / blood
  • Female
  • Humans
  • Hydroxycholecalciferols / blood
  • Infant, Newborn
  • Iran / epidemiology
  • Linear Models
  • Mothers
  • Parathyroid Hormone / blood
  • Pilot Projects
  • Prevalence
  • Prospective Studies
  • Vitamin D Deficiency / blood
  • Vitamin D Deficiency / epidemiology*

Substances

  • Hydroxycholecalciferols
  • Parathyroid Hormone
  • Alkaline Phosphatase
  • Calcium