Urticaria and rhinitis to shrubs of Ficus benjamina and breadfruit in a banana-allergic road worker: evidence for a cross-sensitization between Moracea, banana and latex

Int Arch Allergy Immunol. 2001 Jun;125(2):182-4. doi: 10.1159/000053813.


Background: We report the case of a road worker with a food allergy to banana, who developed urticaria and rhinitis when cutting shrubs of Ficus benjamina and breadfruit. He did not develop an allergy to latex of Hevea brasiliensis.

Results: Sensitization to latex of F. benjamina, H. brasiliensis, breadfruit and banana was demonstrated using skin tests and specific IgE measurements. RAST inhibitions procedures showed that specific IgE to breadfruit latex cross-reacted more strongly with latex of H. brasiliensis and banana than with latex of F. benjamina with the same extract.

Conclusion: Given the wide distribution of Moracea trees in tropical regions, sensitization to latex of H. brasiliensis and banana could be a consequence of sensitization to Moracea members; F. benjamina does not seem to be the only Moracea responsible for cross-allergy with latex and fruit. Consequently, it seems interesting to test other members of the Moracea family in patients sensitized to latex of H. brasiliensis and banana. Sensitization to breadfruit could be a risk factor for sensitization to latex of H. brasiliensis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angioedema / etiology
  • Angioedema / immunology
  • Cross Reactions
  • Dermatitis, Occupational / etiology
  • Dermatitis, Occupational / immunology
  • Food Hypersensitivity / etiology
  • Food Hypersensitivity / immunology*
  • Fruit / adverse effects*
  • Fruit / immunology
  • Humans
  • Immunoglobulin E / immunology
  • Latex / immunology
  • Latex Hypersensitivity / epidemiology
  • Latex Hypersensitivity / immunology*
  • Male
  • Martinique
  • Occupational Diseases / etiology
  • Occupational Diseases / immunology*
  • Plants / adverse effects*
  • Plants / immunology
  • Radioallergosorbent Test
  • Rhinitis, Allergic, Perennial / etiology
  • Rhinitis, Allergic, Perennial / immunology*
  • Risk Factors
  • Skin Tests
  • Trees / immunology
  • Urticaria / etiology
  • Urticaria / immunology*
  • Zingiberales / adverse effects*
  • Zingiberales / immunology


  • Latex
  • Immunoglobulin E