Autistic disorder and schizophrenia: diagnostic overlaps

J Autism Dev Disord. 2001 Feb;31(1):19-28. doi: 10.1023/a:1005605528309.


Data on 14 males with autism and 14 with schizophrenia were collected to examine symptom overlap. The Structured Clinical Interview (SCID), the schedule for positive symptoms (SAPS) and the schedule for negative symptoms (SANS) of schizophrenia, the Childhood Autism Rating Scale (CARS), and the DSM-III-R were administered. On the SCID, none of the men with paranoid schizophrenia met criteria for autism while 7 of those with autism met criteria for schizophrenia, disorganized type, showing negative symptoms. In addition, 5 showed positive symptoms on the SAPS and 6 negative symptoms on the SANS. As the difference in measured nonverbal intelligence was not significant, the effects could not be attributed to it. Although the findings continue to support the differentiation of autism and schizophrenia, they are also consistent with a comorbidity of the two disorders, mainly in those diagnosed with autism.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Autistic Disorder / diagnosis*
  • Autistic Disorder / psychology
  • Diagnosis, Differential
  • Humans
  • Intelligence
  • Male
  • Psychiatric Status Rating Scales / statistics & numerical data
  • Psychometrics
  • Reproducibility of Results
  • Schizophrenia / diagnosis*
  • Schizophrenia, Disorganized / diagnosis
  • Schizophrenia, Disorganized / psychology
  • Schizophrenia, Paranoid / diagnosis
  • Schizophrenia, Paranoid / psychology
  • Schizophrenic Psychology*