Rapid laboratory diagnosis of ulceroglandular tularemia with polymerase chain reaction

Scand J Infect Dis. 2001;33(5):383-5. doi: 10.1080/003655401750174101.

Abstract

Tularemia is a zoonotic disease which, in Scandinavia, is usually acquired through a mosquito bite. As the infecting organism, Francisella tularensis, is highly virulent the culturing of F. tularensis has generally been avoided. PCR offers a safe way to rapidly confirm diagnosis of tularemia. The case of a 9-y-old boy with ulceroglandular tularemia is presented. The diagnosis was made rapidly with DNA amplification from a pus specimen. The efficacy of ciprofloxacin treatment of tularemia in children is also discussed.

Publication types

  • Case Reports

MeSH terms

  • Child
  • DNA, Bacterial / analysis*
  • Francisella tularensis / classification
  • Francisella tularensis / genetics
  • Francisella tularensis / isolation & purification*
  • Humans
  • Lymph Nodes / pathology
  • Male
  • Polymerase Chain Reaction / methods*
  • Skin Ulcer / microbiology
  • Skin Ulcer / pathology
  • Time Factors
  • Tularemia / diagnosis*
  • Tularemia / microbiology
  • Tularemia / physiopathology

Substances

  • DNA, Bacterial