Relationship between oral health and mortality in cardiovascular diseases

J Clin Periodontol. 2001 Aug;28(8):762-8. doi: 10.1034/j.1600-051x.2001.280807.x.
[Article in English, French, German]


Background, aims: The purpose of the study was to investigate the relationship between periodontal health and fatal cardiovascular diseases (CVD).

Methods: The investigation was conducted on a sample of 1393 individuals in the County of Stockholm. The subjects were examined in an epidemiological study in 1970 with respect to dental health. At a follow-up in 1997, the mortality rate of the sample during the years 1970-1996 was registered as well as cause of death according to the death certificate. Stepwise logistic regression analysis was performed in order to evaluate the influence of the investigated variables on the incidence of death from CVD.

Results: The interactional effect between plaque and oral health score (a sum of scores for number of missing teeth, apical lesions, caries lesions and marginal bone loss), adjusted for age, gender, smoking and CVD at baseline, was significantly correlated to fatal coronary events. For individuals younger than 45 years of age, the age-adjusted incidence odds ratio of death due to CVD was 2.7 (p=0.04) if subjects with mean marginal bone loss of >10% were compared with subjects with mean marginal bone loss < or =10 %. If the stratum of individuals <45 years of age is confined to smokers, the odds ratio was found to be 3.4 (p=0.03).

Conclusion: Dental health was found to be a risk indicator of death due to CVD, especially in combination with another risk factor, smoking habits.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Cardiovascular Diseases / mortality*
  • Cause of Death
  • Dental Health Surveys
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Oral Health*
  • Oral Hygiene Index
  • Periodontal Diseases / complications*
  • Periodontal Diseases / mortality
  • Risk Factors
  • Sex Distribution
  • Smoking / mortality
  • Sweden / epidemiology