The effect on intraocular pressure of tracheal intubation or laryngeal mask insertion during sevoflurane anaesthesia in children without the use of muscle relaxants

Paediatr Anaesth. 2001 Jul;11(4):421-4. doi: 10.1046/j.1460-9592.2001.00692.x.


Background: We studied the effects of sevoflurane on intraocular pressure after induction in children undergoing either tracheal tube (TT) or laryngeal mask airway (LMA) insertion without a muscle relaxant

Methods: The study included 38 children. Anaesthesia was induced (8%) and maintained (3-4%) with sevoflurane in 100% O2. No muscle relaxant was used. A TT was inserted in group I (n=20), and an LMA in group II (n=18). IOPs were measured after induction, insertion of TT or LMA and at 1, 2 and 3 min thereafter. The heart rate, mean arterial pressures were also recorded.

Results: Intraocular pressures increased significantly in group I after TT (P < 0.01) and remained high until after 3 min. The pressures were similar in the LMA group at all measurements.

Conclusion: Sevoflurane does not prevent the increase in IOP after intubation without muscle relaxants. LMA does not increase IOP in children after sevoflurane induction.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Anesthesia, Inhalation*
  • Anesthetics, Inhalation*
  • Blood Pressure
  • Child
  • Child, Preschool
  • Female
  • Heart Rate
  • Humans
  • Intraocular Pressure*
  • Intubation, Intratracheal*
  • Laryngeal Masks*
  • Male
  • Methyl Ethers*
  • Neuromuscular Agents / administration & dosage
  • Sevoflurane


  • Anesthetics, Inhalation
  • Methyl Ethers
  • Neuromuscular Agents
  • Sevoflurane