Syndromes involving craniosynostosis and midface hypoplasia

Otolaryngol Clin North Am. 2000 Dec;33(6):1257-84, vi. doi: 10.1016/s0030-6665(05)70280-2.

Abstract

This article reviews a number of well-known syndromes involving craniofacial synostosis and associated midface deficiencies. Syndromes discussed include Apert's, Crouzon's, Saethre-Chotzen, and Carpenter's. Clinical characteristics and genetic defects are discussed. A general approach to surgical management is outlined.

Publication types

  • Review

MeSH terms

  • Acrocephalosyndactylia* / epidemiology
  • Acrocephalosyndactylia* / genetics
  • Acrocephalosyndactylia* / pathology
  • Acrocephalosyndactylia* / therapy
  • Adolescent
  • Craniosynostoses* / epidemiology
  • Craniosynostoses* / genetics
  • Craniosynostoses* / pathology
  • Craniosynostoses* / therapy
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Prevalence
  • Reconstructive Surgical Procedures / methods*