The use of antiplatelet agents in acute cardiac care

Crit Care Clin. 2001 Apr;17(2):365-77, vii. doi: 10.1016/s0749-0704(05)70172-x.

Abstract

Antiplatelet therapy with aspirin has long been established as standard therapy in the management of conditions such as ST-elevation myocardial infarction and the acute coronary syndromes (unstable angina and non-ST-elevation myocardial infarction). Recently, several more potent platelet inhibitors have been developed and tested in randomized clinical trials. This article reviews the current state of the art of antiplatelet therapy.

Publication types

  • Review

MeSH terms

  • Aspirin / adverse effects
  • Aspirin / therapeutic use
  • Clopidogrel
  • Coronary Disease / drug therapy
  • Humans
  • Platelet Aggregation / drug effects*
  • Platelet Aggregation Inhibitors / adverse effects
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Ticlopidine / adverse effects
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / therapeutic use

Substances

  • Platelet Aggregation Inhibitors
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Clopidogrel
  • Ticlopidine
  • Aspirin