Ion homeostasis during salt stress in plants

Curr Opin Cell Biol. 2001 Aug;13(4):399-404. doi: 10.1016/s0955-0674(00)00227-1.


Recent progress has been made in the characterization of cation transporters that maintain ion homeostasis during salt stress in plants. Sodium-proton antiporters at the vacuolar (NHX1) and plasma membrane (SOS1) have been identified in Arabidopsis. SOS1 is regulated by the calcium-activated protein kinase complex SOS2-SOS3. In yeast, a transcription repressor, Sko1, mediates regulation of the sodium-pump ENA1 gene by the Hog1 MAP kinase. The recent visualization at the atomic level of the inhibitory site of sodium in the known target Hal2 has helped identify the interactions determining Na(+) toxicity.

Publication types

  • Review

MeSH terms

  • Adenosine Triphosphatases / metabolism
  • Arabidopsis / metabolism
  • Arabidopsis Proteins*
  • Carrier Proteins / metabolism
  • Cation Transport Proteins*
  • Fungal Proteins / metabolism
  • Homeostasis
  • Ion Transport*
  • Models, Biological
  • Plant Proteins / metabolism
  • Plants / metabolism*
  • Saccharomyces cerevisiae / metabolism
  • Saccharomyces cerevisiae Proteins*
  • Sodium / metabolism*
  • Sodium-Hydrogen Exchangers / metabolism
  • Sodium-Potassium-Exchanging ATPase


  • Arabidopsis Proteins
  • Carrier Proteins
  • Cation Transport Proteins
  • ENA1 protein, S cerevisiae
  • Fungal Proteins
  • NHX1 protein, Arabidopsis
  • NHX1 protein, S cerevisiae
  • Plant Proteins
  • Saccharomyces cerevisiae Proteins
  • Sodium-Hydrogen Exchangers
  • Sodium
  • Adenosine Triphosphatases
  • Sodium-Potassium-Exchanging ATPase