Developmental expression of the Xenopus Iroquois-family homeobox genes, Irx4 and Irx5

Dev Genes Evol. 2001 May;211(5):257-60. doi: 10.1007/s004270100147.

Abstract

We have isolated and characterized the developmental expression of the Xenopus Iroquois 4 (Irx4) and Iroquois 5 (Irx5) homeodomain transcription factors. Irx4 is expressed in a subset of cells in the neural retina and the developing hindbrain and also, specifically, in the ventricle of the heart. Xenopus Irx5 is expressed in the developing midbrain, hindbrain, neural tube, and also in the retina.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Brain / embryology
  • Brain / metabolism
  • Conserved Sequence
  • Gene Expression Regulation, Developmental*
  • Heart / embryology
  • Homeodomain Proteins / genetics*
  • Homeodomain Proteins / physiology
  • Humans
  • Molecular Sequence Data
  • Myocardium / metabolism
  • Retina / embryology
  • Retina / metabolism
  • Sequence Homology, Amino Acid
  • Transcription Factors / genetics*
  • Transcription Factors / physiology
  • Xenopus
  • Xenopus Proteins*
  • Zebrafish
  • Zebrafish Proteins

Substances

  • Homeodomain Proteins
  • IRX4 protein, human
  • IRX5 protein, human
  • Irx4 protein, Xenopus
  • Transcription Factors
  • Xenopus Proteins
  • Zebrafish Proteins
  • irx1a protein, zebrafish