A comparative pilot study of the effects of a dentifrice containing green tea bioflavonoids, sanguinarine or triclosan on oral bacterial biofilm formation

J Clin Dent. 2000;11(2):53-9.

Abstract

The aim of the present study was to evaluate the effect of a green tea bioflavonoid/zinc ascorbate-containing dentifrice (Natural Antioxidant Toothpaste) on bacterial plaque biofilm accumulation. Plaque biofilms were formed and observed on saliva-conditioned synthetic hydroxyapatite disks (HA) over 4 days. Two test treatments were performed daily over a 4-day experimental period for a total of 8 treatments. Four test dentifrices were evaluated: a 0.1% bioflavonoid/0.2% zinc ascorbate; a non-active control test dentifrice; a 0.075% sanguinarine/2.0% zinc chloride dentifrice; and a 0.3% triclosan dentifrice. The repeated treatment of the HA with the green tea bioflavonoid/zinc ascorbate, the sanguinarine/zinc chloride, or the triclosan dentifrice resulted in significant reductions in total viable plaque biomass when compared to a non-active placebo control dentifrice.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / pharmacology
  • Alkaloids / therapeutic use
  • Analysis of Variance
  • Antioxidants / pharmacology
  • Antioxidants / therapeutic use
  • Ascorbic Acid / pharmacology
  • Ascorbic Acid / therapeutic use*
  • Benzophenanthridines
  • Biofilms / drug effects*
  • Complex Mixtures
  • Dental Plaque / prevention & control*
  • Dentifrices / pharmacology
  • Dentifrices / therapeutic use*
  • Durapatite
  • Flavonoids / pharmacology
  • Flavonoids / therapeutic use*
  • Fluorides
  • Isoquinolines
  • Microscopy, Electron, Scanning
  • Phytotherapy
  • Pilot Projects
  • Silicic Acid
  • Streptococcus oralis / drug effects
  • Tea / therapeutic use
  • Toothpastes
  • Triclosan
  • Zinc Compounds / therapeutic use

Substances

  • Alkaloids
  • Antioxidants
  • Benzophenanthridines
  • Complex Mixtures
  • Dentifrices
  • Flavonoids
  • Isoquinolines
  • Tea
  • Toothpastes
  • Zinc Compounds
  • green tea bioflavonoid, zinc ascorbate-containing toothpaste
  • hydrated silica gel-based toothpaste
  • Silicic Acid
  • Triclosan
  • Durapatite
  • sanguinarine
  • Ascorbic Acid
  • Fluorides