Epilepsy and Abnormal Calcium Metabolism in Institutionalized Mentally Retarded Patients

Am J Ment Defic. 1975 May;79(6):738-41.

Abstract

A group of epileptic and nonepileptic patients from an institution for mentally retarded persons was surveyed for roentgenographic and biochemical abnormalities of calcium metabolism. Osteoporosis, hypocalcemia, and increased alkaline phosphatase were found to be significantly increased in incidence in the epileptic group. The only significant difference among the osteoporotic and nonosteoportic epileptic patients was the increase fo the alkaline phosphatase in the former. Ambulation did not appear to influence the significance of the above parameters.

MeSH terms

  • Adolescent
  • Adult
  • Alkaline Phosphatase / blood
  • Anticonvulsants / adverse effects
  • Blood Proteins / analysis
  • Bone Matrix / pathology
  • Calcium / blood
  • Calcium / metabolism*
  • Child
  • Child, Institutionalized
  • Epilepsy / complications
  • Epilepsy / drug therapy
  • Epilepsy / metabolism*
  • Hand / diagnostic imaging
  • Humans
  • Hypocalcemia / chemically induced
  • Intellectual Disability / metabolism*
  • Locomotion
  • Middle Aged
  • Osteoporosis / chemically induced
  • Phosphorus / blood
  • Radiography
  • Wrist / diagnostic imaging

Substances

  • Anticonvulsants
  • Blood Proteins
  • Phosphorus
  • Alkaline Phosphatase
  • Calcium