Immunosuppression was the major factor associated with the deaths of 44 women who died from opportunistic mycotic infections. The patients were immunosuppressed by malignancies, irradiation, cytotoxic drugs, and metabolic diseases. An additional four patients may have developed candidiasis as a result of antibiotic therapy. Coccidoidomycosis was the only mycosis solely associated with pregnancies not altered by exogenous immunosuppression.