Cytokines: IL-20 - a new effector in skin inflammation

Curr Biol. 2001 Jul 10;11(13):R531-4. doi: 10.1016/s0960-9822(01)00312-8.

Abstract

The newly discovered cytokine interleukin-20 (IL-20) is structurally related to IL-10, yet it appears to be an autocrine factor for keratinocytes that regulates their participation in inflammation.

MeSH terms

  • Animals
  • Cell Differentiation
  • Cell Division
  • Epidermis / immunology
  • Epidermis / physiology
  • Interleukin-10 / genetics
  • Interleukins / physiology*
  • Keratinocytes / immunology
  • Mice
  • Mice, Transgenic
  • Models, Immunological
  • Psoriasis / immunology*
  • Receptors, Interleukin / biosynthesis
  • Skin / immunology
  • Up-Regulation

Substances

  • Interleukins
  • Receptors, Interleukin
  • Interleukin-10
  • interleukin 20