The epidemiology of perimenstrual psychological symptoms

Acta Psychiatr Scand. 2001 Aug;104(2):110-6. doi: 10.1034/j.1600-0447.2001.00412.x.


Objective: The purpose of this paper is to examine the prevalence, clinical significance and comorbidity of perimenstrual symptoms/syndrome (PERI-MS) in a community sample of women.

Method: Premenstrual and menstrual physical and psychological symptoms were assessed in a prospective longitudinal study of a representative community cohort of women (N=299) who were interviewed five times between the ages of 21 and 35 years.

Results: When classified according to the severity of distress, the prevalence rates were 8.1% for severe and 13.6% for moderate PERI-MS, respectively. Clinical indicators of severity were all greater among PERI-MS women with than without depressed mood.

Conclusion: The results of this study suggest that irritability, nervousness and tension irrespective of the presence of concomitant depressed mood are core elements of the perimenstrual syndrome.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Affect
  • Anxiety
  • Comorbidity
  • Depression / psychology*
  • Female
  • Humans
  • Longitudinal Studies
  • Premenstrual Syndrome / epidemiology*
  • Premenstrual Syndrome / psychology
  • Prevalence
  • Severity of Illness Index