An introduction to peptide nucleic acid

Curr Issues Mol Biol. 1999;1(1-2):89-104.


Peptide Nucleic Acid (PNA) is a powerful new biomolecular tool with a wide range of important applications. PNA mimics the behaviour of DNA and binds complementary nucleic acid strands. The unique chemical, physical and biological properties of PNA have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors.

Publication types

  • Review

MeSH terms

  • DNA
  • DNA Probes / genetics
  • DNA Probes / metabolism
  • Molecular Structure
  • Nucleic Acid Conformation
  • Peptide Nucleic Acids / chemistry
  • Peptide Nucleic Acids / genetics*
  • Peptide Nucleic Acids / metabolism*
  • Temperature


  • DNA Probes
  • Peptide Nucleic Acids
  • triplex DNA
  • DNA