[A clinical observation on the leukopenia treated with shengbaikuai decoction]

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1998 Jul;18(7):408-10.
[Article in Chinese]


Objective: To study the effective orally taken medicine in treating the leukopenia.

Methods: Ninety cases of leukopenia induced by chemotherapy were divided into 3 groups. They were test group treated with Shengbaikuai Decoction (SBK), control group and blank group. Their efficacies were compared with each other, 25 cases with nonchemotherapy were also observed.

Results: WBC count and absolute neutrophil count (ANC) in test group were higher than those of other groups immediately after treatment and 2 weeks later (P < 0.01). The marked effective rate and total effective rate of test group after 2 weeks were 60.0% and 80.0% (P < 0.001) respectively, which were significantly higher than those of other groups. WBC and ANC count after treatment and 3 weeks later were higher than those before treatment in nonchemotherapy group (P < 0.001). The marked effective rate and total effective rate 3 weeks later were 64.0% and 80.0% respectively.

Conclusions: SBK could increase WBC count rapidly and definitely without apparent side effect.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use
  • Drugs, Chinese Herbal / therapeutic use*
  • Female
  • Humans
  • Leukemia / drug therapy*
  • Leukopenia / chemically induced
  • Leukopenia / drug therapy*
  • Male
  • Middle Aged


  • Antineoplastic Agents
  • Drugs, Chinese Herbal