Abstract
Disseminated intravascular coagulation was induced in dogs by the infusion of a fibrinolytic inhibitor followed by thrombin. The deposition of microthrombi in the lung was demonstrated by radioactive labelling of platelets and fibrinogen.
MeSH terms
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Aminocaproates / pharmacology
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Animals
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Blood Platelets
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Chromium Radioisotopes
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Disseminated Intravascular Coagulation / chemically induced
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Disseminated Intravascular Coagulation / metabolism
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Dogs
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Fibrinogen / metabolism
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Iodine Radioisotopes
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Lung / metabolism
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Male
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Plasma
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Thrombin / pharmacology*
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Time Factors
Substances
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Aminocaproates
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Chromium Radioisotopes
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Iodine Radioisotopes
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Fibrinogen
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Thrombin