Bilateral pallidal stimulation for idiopathic segmental axial dystonia advanced from Meige syndrome refractory to bilateral thalamotomy

Mov Disord. 2001 Jul;16(4):774-7. doi: 10.1002/mds.1122.


Meige syndrome is an adult-onset dystonic movement disorder that predominantly involves facial muscles, while some patients with this syndrome develop spasmodic dysphonia and dystonia of the neck, trunk, arms, and legs. We report that all dystonic symptoms that had been refractory to both pharmacotherapy and bilateral thalamotomy were markedly alleviated by bilateral pallidal stimulation in a patient with segmental axial dystonia advanced from Meige syndrome.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dominance, Cerebral / physiology*
  • Dystonia / diagnosis
  • Dystonia / physiopathology
  • Dystonia / therapy*
  • Electric Stimulation Therapy*
  • Electrodes, Implanted
  • Female
  • Globus Pallidus / physiopathology*
  • Humans
  • Lateral Thalamic Nuclei / physiopathology
  • Lateral Thalamic Nuclei / surgery*
  • Magnetic Resonance Imaging
  • Meige Syndrome / diagnosis
  • Meige Syndrome / physiopathology
  • Meige Syndrome / therapy*
  • Middle Aged
  • Neurologic Examination
  • Treatment Failure