Partial Klüver-Bucy syndrome produced by destroying temporal neocortex or amygdala

Brain Res. 1975 Aug 29;94(2):347-59. doi: 10.1016/0006-8993(75)90067-0.


The temporal neocortex was removed in 4 monkeys, and 5 received amygdala destruction. Four control animals received skin and muscle incisions. The monkeys were compared on a visual pattern discrimination task, a food-non-food discrimination, and a rating scale that measured agonistic and approach behavior. Only the cortical lesion disrupted retention of the visual pattern task and neither lesion disrupted performance of the food-non-food task. Both lesions produced oral behavior, increased reaction to stimuli and decreased emotionality. Thus, the major symptoms of the Klüver-Bucy syndrome are produced by destroying either the temporal neocortex or the amygdala.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amygdala / physiology*
  • Animals
  • Behavior, Animal / physiology*
  • Brain Mapping
  • Cerebral Cortex / physiology*
  • Disease Models, Animal
  • Female
  • Macaca mulatta
  • Male
  • Psychosurgery / adverse effects*
  • Sexual Behavior, Animal / physiology
  • Syndrome
  • Temporal Lobe / physiology*