Cerebello-thalamo-cortical projections to the posterior parietal cortex in the macaque monkey

Neurosci Lett. 2001 Aug 17;309(1):29-32. doi: 10.1016/s0304-3940(01)02018-3.

Abstract

The cerebello-thalamo-posterior parietal cortical projections were investigated electrophysiologically and morphologically in macaque monkeys. In anesthetized monkeys, electrical stimulation of every cerebellar nucleus evoked marked surface-positive, depth-negative (s-P, d-N) cortical field potentials in the superior parietal lobule and the cortical bank of the intraparietal sulcus, but no responses in the inferior parietal lobule. Tract-tracing experiments combining the anterograde method with the retrograde one indicated that the interposed and lateral cerebellar nuclei projected to the posterior parietal cortex mainly through the nucleus ventral lateralis caudalis of the thalamus. The significance of the projections is discussed in connection with cognitive functions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Axonal Transport / drug effects
  • Axonal Transport / physiology
  • Brain Mapping
  • Cerebellar Nuclei / cytology*
  • Cerebellar Nuclei / physiology
  • Electric Stimulation
  • Evoked Potentials / physiology
  • Fluorescent Dyes / pharmacokinetics
  • Macaca / anatomy & histology*
  • Macaca / physiology
  • Neural Pathways / cytology*
  • Neural Pathways / physiology
  • Neurons / cytology*
  • Neurons / physiology
  • Parietal Lobe / cytology*
  • Parietal Lobe / physiology
  • Thalamus / cytology*
  • Thalamus / physiology
  • Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate / pharmacokinetics

Substances

  • Fluorescent Dyes
  • Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate