Abstract
Commercial Thai cobra (Naja kaouthia) antivenom was found to be effective in neutralizing sea snake (Lapemis hardwickii) venom. Neurotoxin specific F(ab')2 fragments obtained from the antivenom by chromatography using Thai cobra neurotoxin or sea snake venom affinity columns were able to neutralize both venoms.
MeSH terms
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Animals
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Antivenins / chemistry
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Antivenins / pharmacology*
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Elapid Venoms / antagonists & inhibitors*
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Elapid Venoms / chemistry
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Elapid Venoms / pharmacology*
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Elapid Venoms / toxicity
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Elapidae
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Immunodiffusion
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Lethal Dose 50
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Mice
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Peptide Fragments / chemistry
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Toxicity Tests
Substances
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Antivenins
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Elapid Venoms
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Peptide Fragments