The Coxibs, Selective Inhibitors of cyclooxygenase-2

N Engl J Med. 2001 Aug 9;345(6):433-42. doi: 10.1056/NEJM200108093450607.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Arthritis / drug therapy*
  • Cardiovascular Diseases / prevention & control
  • Celecoxib
  • Cyclooxygenase 2
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors / adverse effects
  • Cyclooxygenase Inhibitors / pharmacokinetics
  • Cyclooxygenase Inhibitors / therapeutic use*
  • Drug Interactions
  • Female
  • Gastrointestinal Diseases / chemically induced
  • Humans
  • Isoenzymes / antagonists & inhibitors*
  • Kidney / drug effects
  • Lactones / adverse effects
  • Lactones / pharmacokinetics
  • Lactones / therapeutic use*
  • Male
  • Membrane Proteins
  • Prostaglandin-Endoperoxide Synthases
  • Pyrazoles
  • Sulfonamides / adverse effects
  • Sulfonamides / pharmacokinetics
  • Sulfonamides / therapeutic use*
  • Sulfones
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors
  • Isoenzymes
  • Lactones
  • Membrane Proteins
  • Pyrazoles
  • Sulfonamides
  • Sulfones
  • rofecoxib
  • Cyclooxygenase 2
  • PTGS2 protein, human
  • Prostaglandin-Endoperoxide Synthases
  • Celecoxib