Effect of bilateral stimulation of the subthalamic nucleus on parkinsonian voice

Brain Lang. 2001 Aug;78(2):233-40. doi: 10.1006/brln.2001.2466.

Abstract

The purpose of this study was to assess several acoustic features of the voices of 26 parkinsonian patients under two conditions, with and without bilateral chronic stimulation of the subthalamic nucleus (STN) to estimate the effectiveness of this procedure on parkinsonian speech. When compared to unstimulated patients, stimulated patients showed longer duration of sustained vowels, shorter duration of sentences, nonsense words, and pauses, more variable fundamental frequency (f0) in sentences, and more stable f0 during sustained vowels. Relative intensity was unchanged in both conditions. Further acoustic analyses are warranted to clarify the role of STN stimulation on parkinsonian speech.

Publication types

  • Clinical Trial

MeSH terms

  • Dysarthria / diagnosis*
  • Dysarthria / etiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease / complications*
  • Parkinson Disease / diagnosis
  • Parkinson Disease / surgery*
  • Phonetics
  • Severity of Illness Index
  • Speech Acoustics
  • Stereotaxic Techniques
  • Subthalamic Nucleus / surgery*
  • Time Factors
  • Treatment Outcome
  • Voice Quality*