The Amblyopia Treatment Index

J AAPOS. 2001 Aug;5(4):250-4. doi: 10.1067/mpa.2001.117097.


Objective: To develop a questionnaire to assess the acceptability of amblyopia treatment and its effect on the child and family.

Methods: A 20-item parental survey was developed and pilot tested on 64 subjects, aged 3 to 6 years, participating in the Amblyopia Treatment Study, a randomized trial comparing patching and atropine as treatments for moderate amblyopia. The survey was administered after 4 weeks of treatment. A descriptive item analysis and an internal consistency reliability analysis were performed.

Results: Nineteen of the 20 items demonstrated adequate variability as evidenced by the frequency distributions for item responses. Only 4 (<1%) of 1280 possible item responses were missing, one each by 4 different respondents. Factor analysis identified 3 treatment-related factors--"adverse effects," "compliance," and "social stigma"--among 11 of the 20 items. The internal-consistency reliability alpha for the 5-item adverse effects subscale was 0.82, the 4-item compliance subscale alpha was 0.81, and the 2-item social stigma subscale alpha was 0.84.

Conclusions: The Amblyopia Treatment Index appears to be a useful instrument for assessing the impact of amblyopia treatment in 3- to 6-year-old children.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amblyopia / physiopathology
  • Amblyopia / therapy*
  • Atropine / therapeutic use*
  • Child
  • Child, Preschool
  • Female
  • Health Status Indicators*
  • Humans
  • Male
  • Mydriatics / therapeutic use*
  • Patient Compliance
  • Pilot Projects
  • Reproducibility of Results
  • Sensory Deprivation*
  • Surveys and Questionnaires
  • Treatment Outcome


  • Mydriatics
  • Atropine