Abstract
A patient with rheumatoid arthritis developed an acute intrahepatic cholestasis after 100 mg of sodium aurothiomalate. Hepatotoxicity in rheumatoid arthritis is well described following a variety of anti-inflammatory preparations but is now a rare complication of gold therapy and the literature on the subject is reviewed.
MeSH terms
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Arthritis, Rheumatoid / drug therapy
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Biopsy
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Chemical and Drug Induced Liver Injury / etiology*
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Chemical and Drug Induced Liver Injury / pathology
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Cholestasis, Intrahepatic / chemically induced*
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Cholestasis, Intrahepatic / pathology
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Gold Sodium Thiomalate / adverse effects*
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Gold Sodium Thiomalate / therapeutic use
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Humans
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Liver / pathology
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Male
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Middle Aged