Micronutrients: oxidant/antioxidant status

Br J Nutr. 2001 May;85 Suppl 2:S67-74.

Abstract

Potentially damaging species (reactive oxygen, nitrogen and chlorine species) arise as by-products of metabolism and as physiological mediators and signalling molecules. Levels of these species are controlled by the antioxidant defence system. Several components of this system are micronutrients (e.g. vitamins C and E) or are dependent upon dietary micronutrients (e.g. CuZn and Mn superoxide dismutase). The antioxidant defences act as a coordinated system where deficiencies in one component may affect the efficiency of the others. Oxidative stress may be an important factor in infection if micronutrients are deficient.

Publication types

  • Review

MeSH terms

  • Antioxidants / metabolism*
  • Arthritis, Rheumatoid / etiology
  • Ascorbic Acid / adverse effects
  • Ascorbic Acid / physiology
  • Cardiovascular Diseases / etiology
  • Copper / adverse effects
  • Copper / physiology
  • Deficiency Diseases / metabolism*
  • Developing Countries*
  • Disease Susceptibility
  • HIV Infections / metabolism
  • Humans
  • Iron / adverse effects
  • Iron / metabolism
  • Magnesium / physiology
  • Manganese / physiology
  • Micronutrients / physiology*
  • Nutritional Status*
  • Oxidative Stress
  • Virus Diseases / metabolism
  • Vitamin E / physiology
  • Zinc / physiology

Substances

  • Antioxidants
  • Micronutrients
  • Vitamin E
  • Manganese
  • Copper
  • Iron
  • Magnesium
  • Zinc
  • Ascorbic Acid