Renal disease in pregnancy

Obstet Gynecol Clin North Am. 2001 Sep;28(3):593-600, vii. doi: 10.1016/s0889-8545(05)70220-5.


Women with renal disease who conceive and continue a pregnancy are at significant risk for adverse maternal and fetal outcomes. Risk is inversely related to the degree of renal insufficiency. Pregnancy-induced changes in the urinary tract can temporarily increase renal function compromise, such as nephrosis, but most often results in no net increase in dysfunction. Common complications of pregnancy--such as hypertension and hypovolemia--can be associated with acute renal injury or aggravation of pre-existing disease.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Kidney / physiology
  • Kidney Failure, Chronic* / complications
  • Kidney Failure, Chronic* / physiopathology
  • Preconception Care
  • Pregnancy / physiology
  • Pregnancy Complications* / physiopathology
  • Pregnancy Outcome
  • Prenatal Care