Murine natural killer cell activation receptors

Immunol Rev. 2001 Jun;181:115-25. doi: 10.1034/j.1600-065x.2001.1810109.x.

Abstract

Natural killer (NK) cells express two types of receptors involved in target recognition: inhibitory receptors for target cell MHC class I molecules and activation receptors. While there has been significant progress in understanding the inhibitory receptors, less is known about the activation receptors. Detailed analysis of several mouse NK-cell activation receptors provides insight into the physiologic relevance of these receptors in the innate immune response.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Antigens, Ly*
  • Gene Expression
  • Humans
  • Killer Cells, Natural / immunology*
  • Lectins, C-Type
  • Membrane Glycoproteins / genetics
  • Membrane Glycoproteins / metabolism
  • Mice
  • Receptors, Immunologic / genetics
  • Receptors, Immunologic / metabolism*
  • Receptors, NK Cell Lectin-Like
  • Species Specificity

Substances

  • Antigens, Ly
  • Lectins, C-Type
  • Membrane Glycoproteins
  • Receptors, Immunologic
  • Receptors, NK Cell Lectin-Like