A literature review of various reports sponsored by federal governmental agencies and proceedings of conferences of Asian Americans' and Pacific Islanders' health organizations provides data of health disparities among and between these diverse ethnic groups. Specifically, demographic and socio-economic data, as well as health care issues, are reported. Asian Americans and Pacific Islanders exceed other groups in health disparities in the area of tuberculosis and hepatitis B, whereas cancer and cardiovascular diseases are leading causes of death within the Asian American and Pacific Islander populations. Recommendations for areas of research are provided.