A three-year-old male bearded collie was presented with a history of left thoracic limb lameness and a fluctuant non-painful swelling within the flexor tendons of the left carpus. Investigations included ultrasonography, laboratory analysis of fluid aspirated from the lesion and positive contrast radiography. Treatment involved surgical resection of the lesion from the local flexor muscles of the carpus. Histologically, the resected tissue was considered to represent a vascular hamartoma associated with the pronator quadratus muscle.