[Brain stem and cerebellar atrophy in neurosyphilis]

Nervenarzt. 2001 Aug;72(8):647-51. doi: 10.1007/s001150170067.
[Article in German]


A 54-year-old man suffered from serologically proven neurosyphilis with tetraspastic syndrome and bladder dysfunction. He showed a pronounced psychopathy with cognitive decline and attention/concentration deficits. MRI showed slowly progressive cerebellar and brainstem atrophy, which has rarely been described over the past decades. During times of higher incidence and prevalence of neurosyphilis, infratentorial atrophy had been described occasionally, but today this clinical manifestation has been all but forgotten.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Atrophy
  • Brain Stem / pathology*
  • Cerebellum / pathology*
  • Diagnosis, Differential
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Neurocognitive Disorders / diagnosis
  • Neurologic Examination
  • Neuropsychological Tests
  • Neurosyphilis / diagnosis*