Effect of a bicarbonate-containing dentifrice on pH changes in a gel-stabilized plaque after exposure to sucrose

Compend Contin Educ Dent Suppl. 1996;17(19):S8-10.


Because many factors influence the acid-forming ability of dental plaque in the mouth, a model system was used in which reproducible Stephan curves could be generated after exposure of a gel-stabilized plaque to sucrose. Simulation of the use of a high-bicarbonate dentifrice at a time when plaque pH had fallen to about 4.5 caused a rapid return of the pH toward neutrality, whereas simulation of the use of a low-bicarbonate dentifrice had much less effect.

MeSH terms

  • Acids
  • Analysis of Variance
  • Dental Plaque / physiopathology*
  • Dentifrices / therapeutic use*
  • Humans
  • Hydrogen-Ion Concentration
  • Reproducibility of Results
  • Saliva, Artificial / pharmacology
  • Sodium Bicarbonate / therapeutic use*
  • Sucrose / administration & dosage
  • Sucrose / pharmacology*
  • Time Factors


  • Acids
  • Dentifrices
  • Saliva, Artificial
  • Sucrose
  • Sodium Bicarbonate