Review
doi: 10.1038/35089568.
Evolutionary conservation between budding yeast and human kinetochores
Affiliations
- PMID: 11533725
- DOI: 10.1038/35089568
Item in Clipboard
Review
Evolutionary conservation between budding yeast and human kinetochores
Nat Rev Mol Cell Biol.
2001 Sep.
Abstract
Accurate chromosome segregation during mitosis requires the correct assembly of kinetochores--complexes of centromeric DNA and proteins that link chromosomes to spindle microtubules. Studies on the kinetochore of the budding yeast Saccharomyces cerevisiae have revealed functionally novel components of the kinetochore and its regulatory complexes, some of which are highly conserved in humans.
Similar articles
-
A conserved protein, Nuf2, is implicated in connecting the centromere to the spindle during chromosome segregation: a link between the kinetochore function and the spindle checkpoint.Chromosoma. 2001 Sep;110(5):322-34. doi: 10.1007/s004120100153. Chromosoma. 2001. PMID: 11685532
-
Molecular architecture of the kinetochore-microtubule interface.Nat Rev Mol Cell Biol. 2008 Jan;9(1):33-46. doi: 10.1038/nrm2310. Nat Rev Mol Cell Biol. 2008. PMID: 18097444 Review.
-
Structure, function, and regulation of budding yeast kinetochores.Annu Rev Cell Dev Biol. 2003;19:519-39. doi: 10.1146/annurev.cellbio.19.111301.155607. Annu Rev Cell Dev Biol. 2003. PMID: 14570580 Review.
-
Three-dimensional electron microscopy analysis of ndc10-1 mutant reveals an aberrant organization of the mitotic spindle and spindle pole body defects in Saccharomyces cerevisiae.J Struct Biol. 2008 Jul;163(1):18-28. doi: 10.1016/j.jsb.2008.03.015. Epub 2008 Apr 14. J Struct Biol. 2008. PMID: 18515145
-
Chromosome segregation: seeing is believing.Curr Biol. 2005 Jul 12;15(13):R500-3. doi: 10.1016/j.cub.2005.06.033. Curr Biol. 2005. PMID: 16005281 Review.
Cited by
-
KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans.Genes Dev. 2003 Oct 1;17(19):2421-35. doi: 10.1101/gad.1126303. Genes Dev. 2003. PMID: 14522947 Free PMC article.
-
Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore.Genes Dev. 2002 Jan 1;16(1):101-13. doi: 10.1101/gad.949302. Genes Dev. 2002. PMID: 11782448 Free PMC article.
-
Chl4p and iml3p are two new members of the budding yeast outer kinetochore.Mol Biol Cell. 2003 Feb;14(2):460-76. doi: 10.1091/mbc.e02-08-0517. Mol Biol Cell. 2003. PMID: 12589047 Free PMC article.
-
EWSR1 maintains centromere identity.Cell Rep. 2023 Jun 27;42(6):112568. doi: 10.1016/j.celrep.2023.112568. Epub 2023 May 25. Cell Rep. 2023. PMID: 37243594 Free PMC article.
-
Crystal structure of the yeast inner kinetochore subunit Cep3p.Structure. 2007 Nov;15(11):1422-30. doi: 10.1016/j.str.2007.09.008. Structure. 2007. PMID: 17997968 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
