Investigation of the allergenicity of a refined peanut oil-containing topical dermatologic agent in persons who are sensitive to peanuts

Cutis. 2001 Aug;68(2):153-5.


We determined if a topical oil containing 0.01% fluocinolone and refined peanut oil (Derma-Smoothe/FS topical oil), among other ingredients, included materials to which peanut-sensitive individuals were sensitized. No immediate (15-min) or delayed (72-h) skin test reactivity was demonstrated in any of the 14 subjects tested. These results suggest that this refined peanut oil-containing dermatologic preparation is safe to use, even in persons who are sensitive to peanuts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Topical
  • Adolescent
  • Adult
  • Child
  • Dermatologic Agents / administration & dosage
  • Dermatologic Agents / adverse effects*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Patch Tests
  • Peanut Hypersensitivity / diagnosis
  • Peanut Hypersensitivity / immunology*
  • Plant Oils / administration & dosage
  • Plant Oils / adverse effects*
  • Prospective Studies
  • Risk Assessment
  • Sensitivity and Specificity


  • Dermatologic Agents
  • Plant Oils