Structure and function of the homeotic gene complex (HOM-C) in the beetle, Tribolium castaneum

Bioessays. 1993 Jul;15(7):439-44. doi: 10.1002/bies.950150702.


The powerful combination of genetic, developmental and molecular approaches possible with the fruit fly, Drosophila melanogaster, has led to a profound understanding of the genetic control of early developmental events. However, Drosophila is a highly specialized long germ insect, and the mechanisms controlling its early development may not be typical of insects or Arthropods in general. The beetle, Tribolium castaneum, offers a similar opportunity to integrate high resolution genetic analysis with the developmental/molecular approaches currently used in other organisms. Early results document significant differences between insect orders in the functions of genes responsible for establishing developmental commitments.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Drosophila / genetics*
  • Drosophila / growth & development
  • Drosophila / physiology
  • Evolution, Molecular
  • Genes, Homeobox / physiology*
  • Genes, Insect / physiology*
  • Mutation / physiology
  • Tribolium / genetics*
  • Tribolium / growth & development
  • Tribolium / physiology