Fractal landscape analysis of DNA walks

Physica A. 1992 Dec 15;191(1-4):25-9. doi: 10.1016/0378-4371(92)90500-p.

Abstract

By mapping nucleotide sequences onto a "DNA walk", we uncovered remarkably long-range power law correlations [Nature 356 (1992) 168] that imply a new scale invariant property of DNA. We found such long-range correlations in intron-containing genes and in non-transcribed regulatory DNA sequences, but not in cDNA sequences or intron-less genes. In this paper, we present more explicit evidences to support our findings.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • DNA / genetics*
  • DNA, Complementary / genetics
  • Fractals*
  • Humans
  • Introns
  • Models, Biological
  • Models, Genetic*
  • Regulatory Sequences, Nucleic Acid
  • Sequence Analysis, DNA*

Substances

  • DNA, Complementary
  • DNA