Lower body negative pressure as a countermeasure against orthostatic intolerance for long term space flight

A Guell; A Cornac; M M Faurat; G Gauquelin; A Pavy-Le Traon; C l Gharib

doi:10.1016/0094-5765(92)90185-l

Lower body negative pressure as a countermeasure against orthostatic intolerance for long term space flight

Acta Astronaut. 1992 Jul:27:103-7. doi: 10.1016/0094-5765(92)90185-l.

Authors

A Guell¹, A Cornac, M M Faurat, G Gauquelin, A Pavy-Le Traon, C l Gharib

Affiliation

¹ MEDES, Toulouse, France.

PMID: 11537573
DOI: 10.1016/0094-5765(92)90185-l

Abstract

NASA: The effectiveness of lower body negative pressure (LBNP) as a countermeasure against orthostatic intolerance associated with bed rest was investigated. Subjects were exposed to antiorthostatic bedrest at 6 degrees head down tilt, with some exposed to LBNP and some exposed to LBNP with exercise during the bedrest period. Tilt table tests were then performed on all subjects, with heart rate and blood pressure measurements taken. Exposure to LBNP seemed effective in preventing syncope in subjects exposed to bedrest. These results are discussed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Bed Rest / adverse effects*
Blood Pressure / physiology*
Exercise / physiology
Head-Down Tilt / adverse effects
Heart Rate / physiology*
Humans
Hypotension, Orthostatic / etiology
Hypotension, Orthostatic / physiopathology
Hypotension, Orthostatic / prevention & control*
Lower Body Negative Pressure*
Space Flight
Syncope, Vasovagal / etiology
Syncope, Vasovagal / physiopathology
Syncope, Vasovagal / prevention & control*
Tilt-Table Test
Weightlessness / adverse effects
Weightlessness Countermeasures
Weightlessness Simulation