Study of periodontal disease and coenzyme Q

Res Commun Chem Pathol Pharmacol. 1975 Jun;11(2):265-71.


A 25-year old Caucasian with uniquely severe and chronic periodontal disease, requiring extraction of all teeth, was treated with hexahydrocoenzyme Q4 which functions like naturally occurring coenzyme Q10 in gingival tissue. During the fourth and fifth examinations after the seventh and eighth weeks of treatment, three dentists separately and independently scored clinical improvements of five symptoms by significances of essentially P less than 0.01 to P less than 0.001. The initial benefit of the treatment was observed at the second examination after three weeks of treatment. The administration of coenzyme Q could be an important therapeutic adjunct to periodontal therapy for certain patients.

MeSH terms

  • Adult
  • Humans
  • Male
  • Periodontitis / drug therapy*
  • Periodontitis / pathology
  • Time Factors
  • Ubiquinone / therapeutic use*


  • Ubiquinone