Enteropancreatic circulation of digestive enzymes

Science. 1975 Aug 8;189(4201):472-4. doi: 10.1126/science.1154022.

Abstract

Intact digestive enzymes can be absorbed by the intestine and resecreted by the pancreas. The pancreas, therefore, appears to be able to recycle proteins much as the liver recycles bile salts, although the magnitude of this process remains uncertain.

MeSH terms

  • Amylases / metabolism
  • Animals
  • Chymotrypsinogen / metabolism*
  • Duodenum / metabolism
  • Ileum / metabolism
  • In Vitro Techniques
  • Intestine, Small / metabolism*
  • Pancreas / metabolism*
  • Rabbits

Substances

  • Chymotrypsinogen
  • Amylases