Auxin-cytokinin interactions in higher plants: old problems and new tools

Trends Plant Sci. 1997 Sep;2(9):351-6. doi: 10.1016/S1360-1385(97)84623-7.


The plant hormones auxin and cytokinin interact in a complex manner to control many aspects of growth and differentiation. Recent advances in understanding their metabolism and the cell cycle are now helping to clarify the mechanisms by which these hormones act together to control various physiological and developmental responses. Molecular and genetic tools are being used to reveal interactions between auxin and cytokinin at multiple levels, including mutual regulation of active hormone availability, input into multiple signal transduction pathways, alteration of gene expression, post-translational modifications and direct modulation of enzyme activity.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Cell Cycle / drug effects
  • Cell Cycle / physiology
  • Cell Division / drug effects
  • Cell Division / physiology
  • Cytokinins / genetics
  • Cytokinins / metabolism*
  • Cytokinins / pharmacology
  • Gene Expression Regulation, Plant / drug effects
  • Gene Expression Regulation, Plant / physiology*
  • Genes, Plant*
  • Indoleacetic Acids / genetics
  • Indoleacetic Acids / metabolism*
  • Indoleacetic Acids / pharmacology
  • Plant Cells
  • Plant Development
  • Plant Growth Regulators / genetics
  • Plant Growth Regulators / metabolism*
  • Plant Growth Regulators / pharmacology
  • Plant Physiological Phenomena
  • Plants / genetics
  • Plants / metabolism
  • Signal Transduction


  • Cytokinins
  • Indoleacetic Acids
  • Plant Growth Regulators
  • indoleacetic acid