Comparative biological activity study on Passiflora incarnata and P. edulis

K Dhawan; S Kumar; A Sharma

doi:10.1016/s0367-326x(01)00306-9

Comparative biological activity study on Passiflora incarnata and P. edulis

Fitoterapia. 2001 Aug;72(6):698-702. doi: 10.1016/s0367-326x(01)00306-9.

Authors

K Dhawan¹, S Kumar, A Sharma

Affiliation

¹ Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India.

PMID: 11543974
DOI: 10.1016/s0367-326x(01)00306-9

Abstract

The correct identity of Passiflora incarnata and P. edulis was recently established using various parameters. To strengthen these findings, the anxiolytic activity of these two controversial plants has been comparatively investigated. The methanol extract of P. incarnata exhibited significant anxiolytic activity at an oral dose of 125 mg/kg, whereas P. edulis was devoid of any significant activity.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anti-Anxiety Agents / administration & dosage
Anti-Anxiety Agents / pharmacology*
Behavior, Animal / drug effects*
Dose-Response Relationship, Drug
Female
Male
Maze Learning / drug effects*
Mice
Passiflora*
Plant Extracts / administration & dosage
Plant Extracts / pharmacology*
Specific Pathogen-Free Organisms

Substances

Anti-Anxiety Agents
Plant Extracts