Comparative biological activity study on Passiflora incarnata and P. edulis

Fitoterapia. 2001 Aug;72(6):698-702. doi: 10.1016/s0367-326x(01)00306-9.


The correct identity of Passiflora incarnata and P. edulis was recently established using various parameters. To strengthen these findings, the anxiolytic activity of these two controversial plants has been comparatively investigated. The methanol extract of P. incarnata exhibited significant anxiolytic activity at an oral dose of 125 mg/kg, whereas P. edulis was devoid of any significant activity.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Anxiety Agents / administration & dosage
  • Anti-Anxiety Agents / pharmacology*
  • Behavior, Animal / drug effects*
  • Dose-Response Relationship, Drug
  • Female
  • Male
  • Maze Learning / drug effects*
  • Mice
  • Passiflora*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Specific Pathogen-Free Organisms


  • Anti-Anxiety Agents
  • Plant Extracts