Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2001 Sep;108(3):369-74.
doi: 10.1067/mai.2001.117799.

Effectiveness of Laundry Washing Agents and Conditions in the Removal of Cat and Dust Mite Allergen From Bedding Dust

Affiliations

Effectiveness of Laundry Washing Agents and Conditions in the Removal of Cat and Dust Mite Allergen From Bedding Dust

E R Tovey et al. J Allergy Clin Immunol. .

Abstract

Background: There is limited information about the removal of allergens by laundry washing.

Objective: The purpose of this investigation was to determine the dynamics of the removal of mite allergen (Der p 1) and cat allergen (Fel d 1) from bed dust during simulated laundry processes.

Methods: Three studies were performed. The first compared combinations of 4 laundry agents (water alone, soap, detergent with enzymes, and detergent without enzymes), 4 temperatures (15 degrees, 25 degrees, 45 degrees, and 60 degrees C), and 3 extraction times (5, 20, and 60 minutes). The second study examined allergen extraction by 11 common brands of detergents at 25 degrees and 45 degrees C for 5 minutes. The third study compared 4 detergents containing enzymes before and after the denaturation of their enzymes. To measure the quantity of allergens extracted, each study used an ELISA assay as well as a more sensitive but semiquantitative Halogen immunoassay to detect any allergens remaining after the simulated laundry extraction.

Results: Study 1 showed that detergents extracted more of both Fel d 1 and Der p 1 than either soap or water alone and that almost all allergens were extracted within 5 minutes at 25 degrees. However, washing at 60 degrees C extracted slightly more Fel d 1 and denatured Der p 1, resulting in lower residual amounts of both allergens. Study 2 showed that all of the commercial detergents performed similarly. Study 3 showed that the presence of enzymes in detergent formulations did not produce a significant effect on the extraction of allergens.

Conclusion: Using detergent solutions at 25 degrees for at least 5 minutes was sufficient to extract most mite and cat allergen from dust of bedding.

Similar articles

See all similar articles

Cited by 4 articles

  • Environmental control measures for the management of atopy.
    Dilley MA, Phipatanakul W. Dilley MA, et al. Ann Allergy Asthma Immunol. 2017 Feb;118(2):154-160. doi: 10.1016/j.anai.2015.12.029. Ann Allergy Asthma Immunol. 2017. PMID: 28153081 Free PMC article. Review. No abstract available.
  • Environmental assessment and exposure control of dust mites: a practice parameter.
    Portnoy J, Miller JD, Williams PB, Chew GL, Miller JD, Zaitoun F, Phipatanakul W, Kennedy K, Barnes C, Grimes C, Larenas-Linnemann D, Sublett J, Bernstein D, Blessing-Moore J, Khan D, Lang D, Nicklas R, Oppenheimer J, Randolph C, Schuller D, Spector S, Tilles SA, Wallace D; Joint Taskforce on Practice Parameters; Practice Parameter Workgroup. Portnoy J, et al. Ann Allergy Asthma Immunol. 2013 Dec;111(6):465-507. doi: 10.1016/j.anai.2013.09.018. Ann Allergy Asthma Immunol. 2013. PMID: 24267359 Free PMC article. No abstract available.
  • Time for new methods for avoidance of house dust mite and other allergens.
    Tovey E, Ferro A. Tovey E, et al. Curr Allergy Asthma Rep. 2012 Oct;12(5):465-77. doi: 10.1007/s11882-012-0285-0. Curr Allergy Asthma Rep. 2012. PMID: 22833251
  • Allergen avoidance.
    Tovey ER. Tovey ER. Curr Allergy Asthma Rep. 2008 Apr;8(2):126-32. doi: 10.1007/s11882-008-0022-x. Curr Allergy Asthma Rep. 2008. PMID: 18417054 Review.

Publication types

LinkOut - more resources

Feedback