The use of plasma-rich growth factors (PRGF) in oral surgery

Pract Proced Aesthet Dent. 2001 Aug;13(6):487-93; quiz 487-93.


The therapeutic objective of utilizing growth factors in oral surgery is to improve upon the body's regenerative capacity. In many situations, the unaided regeneration process is insufficient to allow complete repair of both bone and soft tissues. This article presents two clinical cases that describe different applications of growth-factor preparation applied at the surgical site in order to stimulate regeneration of osseous and epithelial tissues. Both clinical cases demonstrate the therapeutic effectiveness of utilizing the described technique for the incorporation of plasma-rich growth factors as an adjuvant in regenerative procedure.

Publication types

  • Case Reports

MeSH terms

  • Alveoloplasty / methods*
  • Bone Matrix / transplantation
  • Bone Substitutes / therapeutic use
  • Bone Transplantation / methods*
  • Calcium Chloride / therapeutic use
  • Dental Implantation, Endosseous* / methods
  • Dental Implants
  • Female
  • Humans
  • Male
  • Middle Aged
  • Minerals / therapeutic use
  • Periodontal Pocket / surgery
  • Platelet-Derived Growth Factor / therapeutic use*
  • Tooth Extraction
  • Tooth Fractures / surgery
  • Tooth Mobility / surgery
  • Tooth Root / injuries
  • Transplantation, Autologous
  • Wound Healing


  • Bio-Oss
  • Bone Substitutes
  • Dental Implants
  • Minerals
  • Platelet-Derived Growth Factor
  • Calcium Chloride