Imaging posterior polymorphous corneal dystrophy by in vivo confocal microscopy

Clin Exp Ophthalmol. 2001 Aug;29(4):256-9. doi: 10.1046/j.1442-9071.2001.00432.x.


To identify features of posterior polymorphous dystrophy (PPMD) by in vivo confocal microscopy, the corneas of a female patient with PPMD were exam ned using slit-lamp biomicroscopy and slit-scanning in vivo confocal microscopy. Characteristic endothelial vesicular and band lesions were seen clinically and easily identified using in vivo confocal microscopy. However endothelial pleomorphism, an increased density and reflectance of posterior stromal keratocytes, and prominence of corneal nerves were also delineated. In vivo confocal microscopy enhances clinicopathological diagnosis and follow up of corneal dystrophies with subtle clinical presentations, such as PPMD.

Publication types

  • Case Reports

MeSH terms

  • Corneal Dystrophies, Hereditary / pathology*
  • Corneal Stroma / innervation
  • Endothelium, Corneal / pathology*
  • Female
  • Humans
  • Microscopy, Confocal
  • Middle Aged